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Genital shedding of human immunodeficiency virus type 1 DNA during pregnancy: association with immunosuppression, abnormal cervical or vaginal discharge, and severe vitamin A deficiency
(1997-01)
The presence of human immunodeficiency virus type 1 (HIV-1) in genital secretions may be a determinant of vertical HIV-1 transmission. Cervical and vaginal secretions from HIV-1–seropositive pregnant women were evaluated ...
Effect of breastfeeding on mortality among HIV-1 infected women: a randomised trial.
(2001)
We have completed a randomised clinical trial of breastfeeding and formula feeding to identify the frequency of breastmilk transmission of HIV-1 to infants. However, we also analysed data from this trial to examine the ...
Stable antenatal HIV-1 seroprevalence with high population mobility and marked seroprevalence variation among sentinel sites within Nairobi, Kenya.
(1999)
Objectives: To monitor and analyse trends in HIV-1 seroprevalence among
antenatal women in Nairobi, Kenya.
Design: Six sequential surveys were carried out among antenatal clinic attenders at
four Nairobi City Council ...
Partner Notification Of Pregnant Women Infected With Syphilis In Nairobi, Kenya
(University of Nairobi, 2000-04-11)
We examined partner notification among syphilitic pregnant women in Nairobi. At delivery, 377 women were found to be rapid plasma reagin (RPR) reactive. Data were available for 94% of the partners of women who were tested ...
Health Seeking And Sexual Behaviour Among Primary Health Care Patients In Nairobi, Kenya
(University of Nairobi, 2002)
{ Observational studies have associated vitamin A deficiency with vaginal shedding of human immunodeficiency virus (HIV) type 1-infected cells and mother-to-child HIV-1 transmission. To assess the effect of vitamin A ...
Safety and immunogenicity of recombinant low-dosage HIV-1 A vaccine candidates vectored by plasmid pTHr DNA or modified vaccinia virus Ankara (MVA) in humans in East Africa
(2008)
Summary: The safety and immunogenicity of plasmid pTHr DNA, modified vaccinia virus Ankara
(MVA) human immunodeficiency virus type 1 (HIV-1) vaccine candidates were evaluated in four
Phase I clinical trials in Kenya and ...
Cervical and vaginal shedding of human immunodeficiency virus type 1-infected cells throughout the menstrual cycle
(University of Nairobi, 1998-10)
Cervical and vaginal secretions from 17 women infected with human immunodeficiency virus type 1 (HIV-1) were evaluated daily through the course of one menstrual cycle for HIV-1 DNA (21-31 visits per woman). HIV-1-infected ...
Hormonal contraception, vitamin A deficiency, and other risk factors for shedding of HIV-1 infected cells from the cervix and vagina.
(University of Nairobi, 1997-09)
BACKGROUND: Factors that influence shedding of HIV-1 infected cells in cervical and vaginal secretions may be important determinants of sexual and vertical transmission of the virus. We investigated whether hormonal ...
Mother-child class I HLA concordance increases perinatal human immunodeficiency virus type 1 transmission
(University of Nairobi, 1998-03)
Major histocompatibility complex (MHC) gene products are expressed on human immunodeficiency virus (HIV)-infected cells and incorporated into the lipid envelope of HIV virions. Macaques immunized with human MHC gene products ...
HIV-1 and immunological changes during pregnancy: a comparison between HIV-1-seropositive and HIV-1-seronegative women in Nairobi, Kenya.
(University of Nairobi, 1995-09-09)
OBJECTIVE:
To assess changes in the proportion of CD4 and CD8 T-lymphocyte profiles during pregnancy, at delivery and postpartum, and to determine whether HIV-1 infection affects the normal profile.
DESIGN AND METHODS:
A ...