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Cellular Immune Responses And Susceptibility To HIV-1 Superinfection: A Case-control Study.
(University of Nairobi, 2012-03)
A case-control study was performed to determine the effects of HIV-1-specific cellular immune responses on the odds of acquiring a second HIV-1 infection (superinfection). Changes in the frequency of cytokine-producing or ...
Micronutrient supplementation increases genital tract shedding of HIV-1 in women: results of a randomized trial
(2004)
To test the hypothesis that micronutrient supplementation decreases genital HIV-1 shedding, a double-blind, randomized, placebo-controlled trial of 6 weeks of multivitamin plus selenium supplementation vs. placebo was ...
Vaginal washing and increased risk of HIV-1 acquisition among African women: a 10-year prospective study
(2006)
BACKGROUND:
No prospective study has examined the risk of HIV-1 acquisition associated with vaginal washing, although intravaginal practices have been identified as potentially important contributors to HIV-1 ...
High levels of cervical HIV-1 RNA during early HIV-1 infection.
(2006)
Few data are available on genital tract viral replication early after HIV-1 acquisition, when infectivity is high. We compared cervical HIV-1 RNA from 60 women with paired samples from within 90 days after HIV-1 acquisition ...
Establishing and sustaining a healthy vaginal environment: analysis of data from a randomized trial of periodic presumptive treatment for vaginal infections
(2011)
Data from a randomized trial of oral periodic presumptive treatment (PPT) to reduce vaginal infections were analyzed to assess the effect of the intervention on a healthy vaginal environment (normal flora confirmed by Gram ...
Loss to Follow-Up as a Competing Risk in an Observational Study of HIV-1 Incidence
(2013)
OBJECTIVE:
Conventional survival estimates may be biased if loss to follow-up (LTF) is associated with the outcome of interest. Our goal was to assess whether the association between sexual risk behavior and HIV-1 ...
A decrease in albumin in early HIV type 1 infection predicts subsequent disease progression.
(2007)
We investigated the association between albumin levels and HIV-1 disease progression among 78 Kenyan women followed from before infection through a median of 70 months. With HIV-1 acquisition, median albumin decreased from ...
Understanding the context of HIV risk behavior among HIV-positive and HIV-negative female sex workers and male bar clients following antiretroviral therapy rollout in Mombasa, Kenya.
(2011)
This study explored perceptions of HIV following local introduction of antiretroviral therapy (ART), among 30 HIV-positive and -negative female sex workers (FSWs) and 10 male bar patrons in Mombasa, Kenya. Semi-structured ...
Vitamin A supplementation and human immunodeficiency virus type 1 shedding in women: results of a randomized clinical trial.
(2002)
Observational studies have associated vitamin A deficiency with vaginal shedding of human immunodeficiency virus (HIV) type 1-infected cells and mother-to-child HIV-1 transmission. To assess the effect of vitamin A ...
Improvement of vaginal health for Kenyan women at risk for acquisition of human immunodeficiency virus type 1: results of a randomized trial
(2008)
BACKGROUND:
Vaginal infections are common and have been associated with increased risk for acquisition of human immunodeficiency virus type 1 (HIV-1).
METHODS:
We conducted a randomized trial of directly observed oral ...