Browsing Faculty of Health Sciences (FHS) by Title
Now showing items 4434-4453 of 10378
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HIV-1-specific cellular immune responses among HIV-1-resistant sex workers
(University of NairobiSchool of Public Health Centre for HIV Prevention and Research, 2000)The goal of the present study was to determine whether there were HIV-1 specific cellular immune responses among a subgroup of women within a cohort of Nairobi prostitutes (n = 1800) who, despite their intense sexual ... -
HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi
(Department of Medical Microbiology, 2000)Understanding how individuals with a high degree of HIV exposure avoid persistent infection is paramount to HIV vaccine design. Evidence suggests that mucosal immunity, particularly virus-specific CTL, could be critically ... -
HIV-1-specific mucosal IgA in a cohort of HIV-1-resistant Kenyan sex workers
(Department of Medical Microbiology and Community Health, University of Nairobi, Nairobi, KenyaDivision of Infectious Diseases, Department of Medicine, University of Toronto, Canada,The Cattedra di Immunologia, Universita degli Studi di Milano, Milan, ItalyDepartment of Medical Microbiology, University of Manitoba, Winnipeg, Canada, 1999)Objectives: Most HIV-1 transmission is sexual; therefore, immune responses in the genital mucosa may be important in mediating protection against HIV infection. This study examined HIV-1-specific mucosal IgA in a cohort ... -
HIV-associated fulminating herpes zoster infection with alveolar necrosis and tooth exfoliation: a case report
(University of NairobiDepartment of Oral and Maxillofacial Surgery/Oral Pathology and Oral Medicine, Faculty of Dental Sciences, University of Nairobi, 1997-04)This paper presents a case of HIV-associated fulminating herpes zoster infection (HZI) that culminated in right mandibular necrosis and tooth exfoliation. The occurrence of such infection in immunosuppression and the ... -
HIV-associated fulminating herpes zoster infection with alveolar necrosis and tooth exfoliation: a case report.Dent Update. 1997 Apr;24(3):126-8
(University of Nairobi, 1997)No abstract available -
HIV-associated fulminating herpes zoster infection with alveolar necrosis and tooth exfoliation: a case report.Dent Update. 1997 Apr;24(3):126-8
(University of Nairobi, 1997)No abstract available -
HIV-associated lymphoma: report of three cases.
(Department of Haematology and Blood Transfusion, College of Health Sciences, University of Nairobi, 1999)Persons with congenital or acquired immunosuppression have long been known to have an increased incidence of lymphoproliferative disorders. Unsurprisingly, therefore, the acquired immunodeficiency syndrome (AIDS), caused ... -
HIV-associated malignant lymphomas in Kenya (Equatorial Africa)
(University of Nairobi,, 1998-11)The clinical and pathological features of acquired immune deficiency syndrome (AIDS)-related lymphomas, including their relationship with other viruses, such as Epstein-Barr virus (EBV) and human herpes virus-8 (HHV8), ... -
HIV-associated malignant lymphomas: Nairobi Hospital experienc
(University of Nairobi,Faculty of Medicine, 1999) -
HIV-associated pulmonary hypertension: case report.
(University of Nairobi,College of Health Sciences, 2008)With the advent of highly active antiretroviral therapy, there has been a significant change in the epidemiology of pulmonary disease in HIV/AIDS. The relative prevalence of non-infectious manifestations is likely to rise. ... -
HIV-Exposed seronegative commercial sex workers show a quiescent phenotype in the CD4+ T cell compartment and reduced expression of HIV-dependent host factors
(2010)Studies of human immunodeficiency virus (HIV)–exposed seronegative individuals are crucial to informvaccine design. In the present study we demonstrated that HIV-exposed seronegative commercial sex workers produce lower ... -
HIV-infected women have high numbers of CD103-CD8+ T cells residing close to the basal membrane of the ectocervical epithelium.
(University of Nairobi, 2017)BACKGROUND: Genital mucosa is the main portal of entry for various incoming pathogens, including HIV, hence an important site for host immune defenses. Tissue-resident memory T (TRM) cells defend tissue barriers against ... -
HIV-neutralizing immunoglobulin A and HIV-specific proliferation are independently associated with reduced HIV acquisition in Kenyan sex workers.
(University of Nairobi,College of Health Sciences,, 2008-03)OBJECTIVES: HIV-neutralizing immunoglobulin A (IgA) and HIV-specific cellular immunity have been described in highly exposed, persistently seronegative (HEPS) individuals, but well controlled studies have not been performed. ... -
HIV-Related Deaths in Nairobi, Kenya: Results From a HIV Mortuary Surveillance Study, 2015.
(Kluwer, 2019-05-01)BACKGROUND: Death is an important but often unmeasured endpoint in public health HIV surveillance. We sought to describe HIV among deaths using a novel mortuary-based approach in Nairobi, Kenya. METHODS: Cadavers aged ... -
HIV-related ocular microangiopathic syndrome and neuropsychological functioning.
(University of NairobiCollege of Health Sciences, University of Nairobi, 1993-04) -
HIV-Specific Antibodies Capable of ADCC Are Common in Breastmilk and Are Associated with Reduced Risk of Transmission in Women with High Viral Loads
(Department of Pediatrics, 2012)There are limited data describing the functional characteristics of HIV-1 specific antibodies in breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to bind HIV-1 envelope, neutralize ... -
HIV-Specific Antibodies Capable of ADCC Are Common in Breastmilk and Are Associated with Reduced Risk of Transmission in Women with High Viral Loads
(University of Nairobi, 2012)There are limited data describing the functional characteristics of HIV-1 specific antibodies in breast milk (BM) and their role in breastfeeding transmission. The ability of BM antibodies to bind HIV-1 envelope, neutralize ... -
Hiv-specific Cd8+ T-cell Proliferation Is Prospectively Associated With Delayed Disease Progression.
(University of NairobiDepartment of Medical Microbiology, 2012-03)Human immunodeficiency virus (HIV)-specific CD8(+) T-cell proliferation is consistently correlated with enhanced host HIV immune control, but whether proliferative responses are a cause or consequence of immune protection ... -
Hiv-specific T Cells: Strategies For Fighting A Moving Target.
(University of NairobiDepartment of Medical Microbiology, 2010)HIV vaccine development faces many hurdles, including the failure of empirical approaches, an incomplete understanding of protective immunity, and the extreme genetic diversity of HIV-1. HIV is a moving target in at least ... -
HIV/AIDS and Debt Crises: Threat to human survival in Sub‐Saharan Africa*
(Department of Oral and Maxillofacial Surgery, 2003)Whether originating from the African primates in the Central African forest, or from polio vaccine trials by some western scientists, there is no doubt that HIV/AIDS poses the greatest single challenge to the marginalized ...