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Cytotoxicity of isoflavones from Millettia dura
(University of Nairobi, 2021-08)
The first phytochemical investigation of the flowers of Millettia dura resulted in the isolation of seven isoflavones, a flavonol and a chalcone. Eleven isoflavones and a flavonol isolated from various plant parts from ...
Urine Biomarker Assessment of Infant Adherence to Isoniazid Prophylaxis
(University of Nairobi, 2021)
We assessed adherence in an infant tuberculosis prevention trial in Kenya with a urine isoniazid metabolite-detecting dipstick. Ninety-seven infants had 155 assays performed; 77 (49.7%) were found to be positive despite ...
The 2021-2024 Work Plan of WPA Collaborating Centres
(University of Nairobi, 2021-10)
Prevalence and correlates of common mental health problems and recent suicidal behaviour among female sex workers in Nairobi, Kenya: findings from the Maisha Fiti study
(University of Nairobi, 2021)
Adverse childhood experiences (ACEs), poverty, violence and harmful alcohol/substance are associated with poor mental health outcomes in the general population. These risks are likely to be exacerbated among Female Sex ...
Testing the EPDS and PHQ-9 Among Peripartum Adolescents in Nairobi, Kenya: a Mixed-Methods Study
(University of Nairobi, 2021)
Background:
Cognitive interviewing is a well-recognised methodology to identify clinical and commonsensical relevance of mental health questionnaire items by our research participants. Depression is amongst the most common ...
An Audit of Dorsal Morphology of 30 Adult-Paired Cadaveric Calcaneal Specimen – An Osteological Study
(University of Nairobi, 2020)
Background: The calcaneus exhibits variations of
articular facets and calcaneal sulcus width. These
variations influence occurrence of osteoarthritic
conditions, which have significant prevalence in our
setting, ...
Conceptual framework for establishing the African Stroke Organization
(University of Nairobi, 2020)
Africa is the world's most genetically diverse, second largest, and second most populous continent, with over one billion people distributed across 54 countries. With a 23% lifetime risk of stroke, Africa has some of the ...
Efficacy of phone use on adherence to nevirapine prophylaxis and retention in care among HIV-exposed infants in prevention of mother to child transmission of HIV: a randomized clinical trial
(University of Nairobi, 2021-04)
Background: HIV is a major contributor to infant mortality. A significant gap remains between the uptake of infant and maternal antiretroviral regimens and only a minority of HIV-exposed infants receives prophylaxis and ...
Effect of Bacterial Vaginosis (BV)-HIV-1 Co-existence on Maternal and Infant Health: A Secondary Data Analysis
(University of Nairobi, 2021-03)
Background: The lactobacillus-rich microbiome forms a defense system against infections. Babies are born sterile and acquire their microbiome from exposure to the mothers' vaginal and rectal microbiota. Bacterial vaginosis ...
Prevalence of asymptomatic P. falciparum gametocyte carriage among school children in Mbita, Western Kenya and assessment of the association between gametocyte density, multiplicity of infection and mosquito infection prevalence
(University of Nairobi, 2021-04)
Background: Asymptomatic Plasmodium falciparum gametocyte carriers are reservoirs for sustaining transmission in malaria endemic regions. Gametocyte presence in the host peripheral blood is a predictor of capacity to ...