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Now showing items 71-80 of 83
HIV-1 neutralizing antibody breadth is affected by factors early in infection, but does not influence disease progression. Journal of Virology 83(10):10269-74
(University of Nairobi, 2009)
No abstract available
Low-frequency nevirapine resistance at multiple sites may predict treatment failure in infants on nevirapine-based treatment.
(University of Nairobi., 2012-07)
BACKGROUND:
Resistance commonly arises in infants exposed to single-dose nevirapine (sdNVP) for prevention of mother to child transmission. Although K103N and Y181C are common following sdNVP, multiple other mutations ...
Antiretroviral treatment interruptions predict female genital shedding of genotypically resistant HIV-1 RNA
(University of Nairobi, 2012-08)
Objectives: Resistant viruses may emerge in the female genital tract during antiretroviral therapy (ART). Our objective was to identify predictors of drug-resistant HIV-1 RNA in genital secretions after initiation of ...
Cell-free human immunodeficiency virus type 1 in breast milk
(University of Nairobi, 1998)
Breast-feeding may be an important route of human immunodeficiency virus type 1 (HIV-1) vertical transmission in settings where it is routinely practiced. To define the prevalence and quantity of HIV-1 in cell-free breast ...
The Effect Of Treatment Of Vaginal Infections On Shedding Of Human Immunodeficiency Virus Type 1
(University of Nairobi, 2001)
We evaluated the association between the severity of primary human immunodeficiency virus type 1 (HIV-1) illness and HIV-1 plasma virus load before seroconversion using stored plasma samples obtained from 74 prostitutes ...
Human immunodeficiency virus type 1-infected cells in breast milk: association with immunosuppression and vitamin A deficiency
(1995-12)
Breast milk samples from human immunodeficiency virus type 1 (HIV-1)-seropositive women were analyzed by polymerase chain reaction to determine the prevalence and determinants of HIV-1-infected cells in breast milk. Breast ...
Subtype C Is associated with increased vaginal shedding of HIV-1.
(2005-08-01)
The prevalence of human immunodeficiency virus (HIV)-1-infected cells and HIV-1 RNA levels in genital secretions and breast milk and the risk of mother-to-child transmission of HIV-1 were compared among subtypes A, C, and ...
No evidence for rapid subtype C spread within an epidemic in which multiple subtypes and intersubtype recombinants circulate
(2005)
There are multiple subtypes of HIV-1 circulating worldwide, but recently, subtype C has become highly prevalent, particularly in certain geographic regions. It is unclear whether the dominance of subtype C or other subtypes ...
A prospective study of risk factors for herpes simplex virus type 2 acquisition among high-risk HIV-1 seronegative women in Kenya
(2011)
OBJECTIVES:
Several studies have demonstrated an association between herpes simplex virus type 2 (HSV-2) and HIV-1, but available data on risk factors for HSV-2 acquisition are limited. The objective of this analysis ...
Acute Hiv-1 Infection Illness In Kenyan Women Is Associated With Higher Viral Loads
(University of Nairobi, 2002)