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Subtypes of Human Immunodeficiency Virus Type 1 and Disease Stage among Women in Nairobi, Kenya
(1999)
In sub-Saharan Africa, where the effects of human immunodeficiency virus type 1 (HIV-1) have been most devastating, there are multiple subtypes of this virus. The distribution of different subtypes within African populations ...
The Breadth and Potency of Passively Acquired Human Immunodeficiency Virus Type 1-Specific Neutralizing Antibodies Do Not Correlate with the Risk of Infant Infection[down-pointing small open triangle]
(2011)
Although a major goal of human immunodeficiency virus type 1 (HIV-1) vaccine efforts is to elicit broad and
potent neutralizing antibodies (NAbs), there are no data that directly demonstrate a role for such NAbs in
protection ...
Genital inflammation predicts HIV-1 shedding independent of plasma viral load and systemic inflammation
(2012)
In women, genital HIV-1 RNA levels predict the risk of
HIV-1 transmission independent of plasma viral load. To better
understand the factors that contribute to genital HIV-1 shedding, we
evaluated the relationships ...
Effects of Valcyclovir on markers of disease Progression in Postpartum Women Co-Infected with HIV-1 andHerpes Simplex Virus-2
(2012-06)
Objective:
Herpes simplex virus type 2 (HSV-2) suppression has been shown to reduce HIV-1 disease progression in nonpregnant
women and men, but effects on pregnant and postpartum women have not been described.
Methods:
We ...
Predictors of early mortality in a cohort of human immunodeficiency virus Type 1-infected African Children
(2004)
Background: Pediatric human immunodeficiency virus type 1
(HIV-1) infection follows a bimodal clinical course with rapid
progression in 10–45% of children before the age of 2 years and
slower progression in the remainder. ...
Breast milk HIV-1 suppression and decreased transmission: a randomized trial comparing HIVNET012 nevirapine versus short-course zidovudine
(2005)
Objective: To compare the effect of perinatal regimens of short-course nevirapine
(HIVNET012)andzidovudine[Thai-CentersforDiseaseControlandPrevention(CDC)
regimen] on breast milk viral shedding and perinatal transmission ...
Hormonal contraception and HIV-1 disease progression among postpartum Kenyan women
(2007)
Objective
To assess the immediate and longer-term effects of the use of hormonal contraception on the progression of HIV-1 disease in postpartum women.
Design
A prospective cohort study.
Methods
Information on ...
HIV-1 persists in breast milk cells despite antiretroviral treatment to prevent mother-to-child transmission
(2008)
Background: The effects of short-course antiretrovirals given to reduce mother-to-child
transmission (MTCT) on temporal patterns of cell-associated HIV-1 RNA and DNA in
breast milk are not well defined.
Methods: Women ...
Highly Active Antiretroviral Therapy (HAART) versus Zidovudine/Nevirapine Effects on Early Breast Milk HIV-1 RNA: A Phase II Randomized Clinical Trial
(2008)
Background
Defining the effect of antiretroviral regimens on breast milk HIV-1 levels is useful to inform the rational design of strategies to decrease perinatal HIV-1 transmission.
Methods
Pregnant HIV-1 seropositive ...
HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 Loads
(2007)
We investigated the effect of human immunodeficiency virus
type 1 (HIV-1) subtype on disease progression among 145
Kenyan women followed from the time of HIV-1 acquisition.
Compared with those infected with subtype A, ...