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Validity of the vaginal discharge algorithm among pregnant and non-pregnant women in Nairobi, Kenya
(University of Nairobi., 2000-02)
OBJECTIVE:
To evaluate the validity of different algorithms for the diagnosis of gonococcal and chlamydial infections among pregnant and non-pregnant women consulting health services for vaginal discharge in Nairobi, ...
Loss to Follow-Up as a Competing Risk in an Observational Study of HIV-1 Incidence
(2013)
OBJECTIVE:
Conventional survival estimates may be biased if loss to follow-up (LTF) is associated with the outcome of interest. Our goal was to assess whether the association between sexual risk behavior and HIV-1 ...
Safety and immunogenicity of recombinant low-dosage HIV-1 A vaccine candidates vectored by plasmid pTHr DNA or modified vaccinia virus Ankara (MVA) in humans in East Africa
(2008)
Summary: The safety and immunogenicity of plasmid pTHr DNA, modified vaccinia virus Ankara
(MVA) human immunodeficiency virus type 1 (HIV-1) vaccine candidates were evaluated in four
Phase I clinical trials in Kenya and ...
Increased risk of genital ulcer disease in women during the first month after initiating antiretroviral therapy
Genital ulcer disease (GUD) is common in HIV-1-infected women, and a small number of stu dies have suggested increased GUD risk after antiretroviral therapy (ART) initiation. To better define this risk, we monitored 134 ...
Infection with Trichomonas vaginalis increases the risk of HIV-1 acquisition
(2007)
We conducted a prospective study among women in Mombasa, Kenya, to determine whether Trichomonas vaginalis infection was associated with an increased risk of human immunodeficiency virus type 1 (HIV-1) infection. At monthly ...
Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV-1 shedding among women initiating treatment
(2010)
Persistent genital human immunodeficiency virus type 1
(HIV-1) shedding among women receiving antiretroviral
therapy (ART) may present a transmission risk. We investigated
the associations between genital HIV-1 ...
Genital ulceration does not increase HIV-1 shedding in cervical or vaginal secretions of women taking antiretroviral therapy.
(University of Nairobi, 2011)
OBJECTIVES:
Genital ulcer disease (GUD) is associated with increased HIV-1-RNA shedding in antiretroviral therapy (ART)-naive women. The effect of GUD on HIV-1 shedding among ART-treated women is not known. The objective ...
HIV-1 acquisition and disease progression are associated with decreased high-risk sexual behaviour among Kenyan female sex workers.
(2006)
BACKGROUND:
Changes in sexual risk behaviour may occur following HIV-1 infection.
OBJECTIVE:
To test the hypothesis that HIV-1 seroconversion and disease progression are associated with changes in risk behaviours, ...