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Antimicrobial and antiparasitic abietane diterpenoids from the roots of Clerodendrum eriophyllum
(University of Nairobi, 2010-06)
Chromatographic separation of the roots of a Kenyan medicinal plant, Clerodendrum eriophyllum, led to the isolation of ten abietane diterpenoids (1-10), one of which (1) was isolated for the first time from a natural source. ...
Anti-plasmodial Activities Of Flavonoids From Erythrina Sacleuxii
(University of Nairobi, 2006-02)
The acetone extracts of the root bark and stem bark of Erythrina sacleuxii showed antiplasmodial activities against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum. Chromatographic ...
Flavonoids and Isoflavonoids with Antiplasmodial Activities from the Root Bark of Erythrina abyssinica
(University of Nairobi, 2003-07)
From the root bark of Erythrina abyssinica a new pterocarpene [3-hydroxy-9-methoxy-10-(3,3-dimethylallyl)pterocarpene] and a new isoflav-3-ene [7,4′-dihydroxy-2′,5′-dimethoxyisoflav-3-ene] were isolated. In addition, the ...
Effect of rotenoids from the seeds of Millettia dura on larvae of Aedes aegypti
(University of Nairobi, 2003-10)
A crude chloroform extract of seeds of Millettia dura Dunn (Leguminosae) showed high activity (LC50 = 3.5 µg ml−1 at 24 h) against second-instar larvae of the mosquito, Aedes aegypti L (Diptera: Culicidae). The rotenoids, ...
Antimicrobial flavonoids from the stem bark of Erythrina burttii
(University of Nairobi, 2005-07)
The chloroform extract of the stem bark of Erythrina burttii showed antifungal and antibacterial activities using the disk diffusion method. Flavonoids were identified as the active principles. Activities were observed ...
Flavonoids and isoflavonoids of Erythrina burttii
(2009)
From the stem bark and root bark of Erythrina burttii twenty-three flavonoids and isoflavonoids, including some
eight new compounds, have been isolated and characterised. The stem bark of this plant mainly produces
isoflavanones ...
7a-O-methyldeguelol, a modified rotenoid with an open ring-C, from the roots of Derris trifoliata
(2005-03)
From the acetone extract of the roots of Derris trifoliata an isoflavonoid derivative, named 7a-O-methyldeguelol, a modified rotenoid with an open ring-C, representing a new sub-class of isoflavonoids (the sub-class is ...
Anti-plasmodial activities and X-ray crystal structures of rotenoids from Millettia usaramensis subspecies usaramensis
(University of Nairobi, 2003-10)
The dichloromethane extract of the stem bark of Millettia usaramensis subspecies usaramensis showed anti-plasmodial activity against the chloroquine sensitive (D6) and chloroquine resistant (W2) strains of Plasmodium ...
Anti-plasmodial flavonoids from the stem bark of Erythrina abyssinica
(2004)
The ethyl acetate extract of the stem bark of Erythrina abyssinica showed anti-plasmodial activity against the chloroquine-sensitive (D6) and chloroquine-resistant (W2) strains of Plasmodium falciparum with IC50 values of ...
Two unusual rotenoid derivatives, 7a-O-methyl-12a-hydroxydeguelol and spiro-13-homo-13-oxaelliptone, from the seeds of Derris trifoliata
(2006-05)
The crude methanol extract of the seeds of Derris trifoliata showed potent and dose dependent larvicidal activity against the 2nd instar larvae of Aedes aegypti. From this extract two unusual rotenoid derivatives, a ...