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Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV Exposed, seronegative female sex workers in Kenya
(2012)
Identifying the immune correlates of reduced susceptibility to HIV remains a key goal for the HIV vaccine field, and individuals who are HIV-exposed, seronegative (HESN) may offer important clues. Reduced systemic immune ...
Does antiretroviral therapy initiation increase sexual risk taking in Kenyan female sex workers? A retrospective case–control study
(2012)
Although antiretroviral therapy (ART) prolongs life and reduces infectiousness, in some contexts, it has been associated with increased sexual risk taking.
Design
Retrospective case–control study.
Setting
...
Background Morbidity In HIV Vaccine Trial Participants From Various Geographic Regions As Assessed By Unsolicited Adverse Events
(University of Nairobi, 2012-05)
BACKGROUND:
Recently, more clinical trials are being conducted in Africa and Asia, therefore, background morbidity in the respective populations is of interest. Between 2000 and 2007, the International AIDS Vaccine ...
Epigenetic Control Of Irf1 Responses In HIV-exposed Seronegative Versus HIV-susceptible Individuals.
(University of Nairobi, 2011-03)
Not all individuals exposed to HIV become infected. Understanding why these HIV-exposed seronegative individuals remain uninfected will help inform the development of preventative measures against HIV infection. Interferon ...
Factors associated with resumption of sex before complete wound healing in circumcised HIV-positive and HIV-negative men in Kisumu, Kenya.
(University of Nairobi, 2012-12)
BACKGROUND:: We evaluated time-to-resumption of sex in relation to wound healing following circumcision of adult males. The purpose was to assess factors associated with adherence to the WHO recommendation of 42-days ...
Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV-1 shedding among women initiating treatment
(2010)
Persistent genital human immunodeficiency virus type 1
(HIV-1) shedding among women receiving antiretroviral
therapy (ART) may present a transmission risk. We investigated
the associations between genital HIV-1 ...
Antifungal Susceptibilities of Cryptococcus Neoformans Cerebrospinal fluid Isolates from AIDS Patients in Kenya
(2010)
Poor susceptibility of Cryptococcus neoformans to fluconazole (FLC) is a matter of
concern among clinicians in Africa. The emergence of resistance to FLC was recently
reported in Kenya, but it is not known whether it is ...
Selection, Phenotyping and Identification of Acid and Hydrogen Peroxide Producing Bacteria from Vaginal Samples of Canadian and East African Women
(2012)
The common but poorly understood condition known as bacterial vaginosis (BV) increases vulnerability to HIV infection and is associated with the absence of H(2)O(2)-producing Lactobacillus. Vaginal lactic acid bacteria ...
Treatment with Antiretroviral Therapy is Not Associated with Increased Sexual Risk Behaviour in Kenyan Female Sex Workers
(2010-03)
OBJECTIVE:
The objective of this study was to test the hypothesis that sexual risk behavior would increase following initiation of antiretroviral therapy (ART) in Kenyan female sex workers (FSWs).
DESIGN:
Prospective ...
Time to Complete Wound Healing in HIV-Positive and HIV-Negative Men following Medical Male Circumcision in Kisumu, Kenya: A Prospective Cohort Study
(2013)
Background
While voluntary medical male circumcision (VMMC) has been shown to be protective against HIV-acquisition, the procedure may place men and their partners at risk of HIV infection in the period following ...